Chemistry Journal of Moldova

SYNTHESIS OF PINONIC ACID NEW DERIVATIVES

Author(s):

Alexandru Gudima, Liudmila Vlad, Fliur Macaev


Field: Natural product chemistry and synthesis
Type: Short communication
Issue: 2008 Volume 3, no.2
Pages: 122-123
Keywords:

pinonic acid, chlorohydrin, epoxide.


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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2008.03(2).10

Graphical Abstract:
 The method for synthetising new derivatives of the pinonic acid using, at the key step, the reaction of condensation with epichlorohydrin, has been elaborated. It has been shown that, in the presence of catalytic amount of tetrabutylammonium chloride, the reaction is directed towards the formation of etherchlorohydrin, which, later on, is easily transformed into epoxides as well as chloromethyldiketones with good overall yield.

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