Chemistry Journal of Moldova

(-)-SCLAREOL CONVERSION IN RITTER'S REACTION CONDITIONS

Author(s):

S. Kovalskaya, N. Kozlov, A. Aricu, V. Kulcitki, N. Ungur


Field: Natural product chemistry and synthesis
Type: Short communication
Issue: 2012 Volume 7, no.2
Pages: 147-148
Keywords:

diterpenoids, Ritter’s reaction, diamide, sclareol.


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Abstract (JPEG)

DOI:
dx.doi.org/10.19261/cjm.2012.07(2).01

Graphical Abstract:
 The main products of sclareol (1) Ritter’s reaction in mild conditions are (8R,13R)-Labd-14(15)-en-8,13-diacetamide (2) (8R,13S)-Labd-14(15)-en-8,13-diacetamide (3) stereoisomeric on C13 atom and having unrearranged native diol skeleton. We present in the current communication the results of sclareol converting (1) into nitrogen-containing labdanes
in the Ritter’s reaction conditions.

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