Chemistry Journal of Moldova

MOLECULAR CONCEPTS OF MACROPHAGE TARGETING

Author(s):

Veaceslav Boldescu, Valeriu Crudu, Natalia Sucman, Serghei Pogrebnoi, Marina Zviaghinţeva, Eugenia Stîngaci, Vsevolod Pogrebnoi, Fliur Macaev


Field: Organic chemistry
Type: Review
Issue: 2013 Volume 8, no.2
Pages: 21-31
Keywords:

macrophage receptor targeting, macrophage enzyme targeting, inflammatory disorders, tuberculosis, cancer


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DOI:
dx.doi.org/10.19261/cjm.2013.08(2).02

Graphical Abstract:
Macrophages play an important role in the pathological development of different diseases. Therefore, macrophage targeting represents an important challenge in design of new medicines. This review gives a general presentation of small molecule-recognition concepts used for macrophage targeting. It describes mechanisms and systems for macrophage-targeted delivery, their obtaining and application.



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