Chemistry Journal of Moldova

AN INVESTIGATION OF THE PROTONATION STATES OF HUMAN LACTOFERRIN IRON-BINDING PROTEIN

Author(s):

Lilia Anghel


Field: Physical chemistry and chemical physics
Type: Research paper
Issue: 2015 Volume 10, no.1
Pages: 71-75
Keywords:

lactoferrin, ionizable residues, protonation, continuum electrostatics.


Full Text (PDF): Download
Abstract (PDF)

DOI:
dx.doi.org/10.19261/cjm.2015.10(1).10

Graphical Abstract:
 In this study, the protonation states of ionizable groups of human lactoferrin in various conformations were investigated theoretically, at physiological pH (7.365). These calculations show that the transition of the protein from a conformation to another one is accompanied by changes in the protonation state of specific amino acid residues. 

Downloads: 63