Chemistry Journal of Moldova

Accepted papers

Olga Kazakova, Roman Ivannikov, Iryna Laguta, Oksana Stavinskaya, Viktor Anishchenko, Olga Severinovska, Ludmila Buyun

Field: Physical chemistry and chemical physics
Type: Research paper
orchid extract, phenolic compound, HPLC, fumed silica, quantum chemical calculation.

 
Supplementary Material (PDF)
Graphical Abstract: The most common phenolic components of sixteen orchid extracts were identified using high performance liquid chromatography and laser desorption/ionization mass spectrometry. The interaction between these compounds and silica silanol groups was studied using quantum chemical calculations. Results show that the strength of the interaction of phenols with silica increased in the following order: ferullic, feruloylquinic and fertaric acids < kaempferol, apingenin << сhlorogenic and caffeic acids, rhamnetin, quercetin, luteolin, epicatechin gallate. The common feature of compounds characterized by the strongest interaction with silanol groups is the presence of phenol ring with two neighbouring hydroxyl groups.


 

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Imeda Rubashvili, Natela Karukhnishvili, Khatuna Makharadze

Field: Analytical chemistry
Type: Research paper
13
lisinopril, hydrochlorthiazide, swab sampling, rinse sampling, HPLC, validation.
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Graphical Abstract: A new, rapid and selective, HPLC method for simultaneous quantitative estimation of lisinopril and hydrochlorothiazide residues and sampling procedures from pharmaceutical manufacturing equipment surfaces were developed and validated. The sampling procedures have a good recovery (>80%). The limit of quantitation of the HPLC method - 0.155 µg/mL and 0.025 µg/mL for lisinopril and hydrochlorothiazide, respectively. 


 

Downloads: 19

Syed Sauban Ghani, Aman Deo

Field: Food chemistry
Type: Research paper
7
heavy metal, accumulation, fish, marine environment, Pacific Ocean.
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Graphical Abstract: The concentrations of the accumulated heavy metals such as cadmium, lead, copper, mercury, zinc, and chromium have been determined in the muscles, gills and liver of the fish species of Clupea pallasii, Macolor niger and Pristipomoides filamentosus collected from the waters of the South Pacific Ocean around Lautoka in Fiji. Overall, the contents of heavy metals in all the samples were below the permissible limits, except for chromium that is slightly higher than the limit set by Food and Agriculture Organization of the United Nations and World Health organization regulations respectively. As anticipated, the muscles are still near the lowest concentration of all metal concentration. Significant variations in heavy metal concentrations were found between different tissues within each species of fish.


 

Downloads: 23

Gunel Mamedova

Field: Ecological chemistry
Type: Research paper
10
hydrothermal synthesis, zeolites, gismondine, laumontite, levyne.
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Graphical Abstract: Gismondine, laumontite and levyne type zeolites have been synthesized based on the natural minerals of Nakhchivan and the optimal crystallization conditions have been established. The initial components and the reaction products have been examined by X-ray diffraction, thermogravimetric and elemental analyses. It was found that changes in the temperature, alkalinity, ratio of starting components and time of processing of the reaction have different effects on the rate of formation of products, on their degree of crystallinity and on the phase purity of the obtained zeolite.


 

Downloads: 101

Daniela Guglietta, Girolamo Belardi, Giovanna Cappai, Barbara Casentini, Alicia Godeas, Stefano Milia, Daniele Passeri, Rosamaria Salvatori, Adalgisa Scotti, Vanesa Silvani, Emanuela Tempesta, Stefano Ubaldini, Francesca Trapasso

Field: Ecological chemistry
Type: Research paper
10
mining waste, metal recovery, recycle, remote sensing analysis.
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Graphical Abstract: The aim of this paper is to evaluate an integrated multidisciplinary strategy for the characterization of mining waste, their possible recycling and reuse. The use of Fe-Mn rich wastes in arsenic removal and phosphorus recovery from water and the phytoextraction potential of metals and their possible recovery from biomass are evaluated.


 

Downloads: 36

Koba Amirkhanashvili, Alexandre Sobolev, Nani Zhorzholiani, Vladimer Tsitsishvili

Field: Inorganic and coordination chemistry
Type: Research paper
8
lidocaine complex, X-ray analysis, crystal structure, hydrogen bond.
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Graphical Abstract: This paper reports on the synthesis and structure re-refinement of bis(lidocaine) diaquatetrathiocyanatonickelate(II). The compound with the formula (LidH)2[Ni(NCS)4(H2O)2], where Lid is (2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide, crystallizes in the monoclinic space group P21/c with a= 18.3509(5), b= 7.6532(2), c= 14.9585(4) Å, β= 109.964 (2)°, V= 1974.57 (9) Å3, and Z= 2. Coordination of the Ni2+ ion with thiocyanate ions and water molecules generates slightly distorted octahedral anion [Ni(NCS)4(H2O)2]2–  with N-bonded thiocyanate groups, while two protonated cations LidH+ remain in an outer coordination field. 


 

Downloads: 30

Lauro Figueroa, Alejandra Garcimarero, Rolando Garcia, Francisco Diaz, Marcela Rosas, Virginia Mateu, Maria Lopez, Lenin Hau, Tomas Lopez, Abelardo Camacho, Yaritza Borges

Field: Organic chemistry
Type: Research paper
11
bicyclo, steroid, estrone derivative, synthesis.
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Graphical Abstract: This study describes the preparation of two bicyclo[3.3.3]nonane-steroid derivatives from either estradiol or estrone using some reactions such as etherification, addition, nucleophilic substitution and cyclization. The chemical structure was evaluated through NMR spectroscopic analysis. The results showed higher yield for 11 compared with 12. It is noteworthy that the reagents used in this investigation are not expensive and do not require special conditions for handling.

Downloads: 45

Hajer Hrichi, Nadia Ali Ahmed Elkanzi, Rania Badawy Bakr

Field: Organic chemistry
Type: Research paper
9
heterocycle, β-lactam, quinoxaline, antimicrobial activity, molecular docking.
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Graphical Abstract: A series of novel isolated β-lactams 3a-c and thiazolidinone derivatives 4a-c were successfully synthesized from reactions of new Schiff's bases 2a-c with chloroacetyl chloride and thioglycolic acid. The chemical structures of the new compounds were confirmed through different spectroscopic techniques including IR, 1H NMR, 13C NMR, mass spectrometry and elemental analysis. The antimicrobial activity of the obtained compounds was assessed in-vitro against gram-positive Staphylococcus aureus and gram-negative Escherichia coli bacteria and Aspergillus flavus and Candida albicans fungi. Furthermore, a molecular docking study was carried out and the results indicated that compounds 3b and 4b displayed comparable binding affinity scores as that of glutamate. These two compounds are promising candidates as antibacterial and antifungal agents that would deserve further investigations.



 

Downloads: 49